منابع مشابه
Organelle proteomics.
This unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided. Specific protocols for the isolation of nuclei from various sources (cell cultures, ...
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The need to inherit those membranes that arise from the ER is much less clear. As an example, the integral *Imperial Cancer Research Fund Cell Biology Laboratory membrane proteins and lipids of the Golgi apparatus are derived entirely from the ER. If a daughter did not 44 Lincoln's Inn Fields London WC2A 3PX inherit a copy of the Golgi apparatus, it should be able to synthesize one de novo. Sev...
متن کاملMechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance
Fluctuations in organelle abundance can profoundly limit the precision of cell biological processes from secretion to metabolism. We modeled the dynamics of organelle biogenesis and predicted that organelle abundance fluctuations depend strongly on the specific mechanisms that increase or decrease the number of a given organelle. Our model exactly predicts the size of experimentally measured Go...
متن کاملAn organelle knockout
multipotent skin-derived stem cell, and a purified neural stem cell from the brain have come on the scene at a delicate time in the debate over embryonic stem cell research. Each success in isolating adult stem cells, such as these cells, gives ammunition to opponents of embryonic stem cell research, who point to adult-derived stem cells as an alternative source of transplant-ready material. Th...
متن کاملThe incredible shrinking organelle.
considering its central role in energy metabolism in almost all eukaryotes, the mitochondrion is an amazingly plastic organelle, both evolutionarily and functionally. the few genes that the mitochondrial genome (mito chondrial DNa; mtDNa) encodes are clearly bacterial in origin —emanating from the α-proteobacterial lineage—supporting the widely held view that the mitochondrion is the evolutiona...
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ژورنال
عنوان ژورنال: Cell Structure and Function
سال: 2019
ISSN: 0386-7196,1347-3700
DOI: 10.1247/csf.19010